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Anti-AIM2 antibody
Anti-AIM2 antibody from Abcam
Be the first to write a review!
Citations:
(35)
Supplier Page
Supplier Page from
Abcam for
Anti-AIM2 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-AIM2 antibody
Company
Abcam
Price
Supplier Page
View Supplier Product Page
Catalog Number
ab93015
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Quantity
100 UG
Clonality
Polyclonal
Antibody Type
Primary
Isotype
IgG
Host
Rabbit
Conjugate/Tag
Unconjugated
Concentration
0.5 mg/ml
Gene Name
Aim2
Reactivity
Human
Target
AIM2
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (35)
(1)
Epigallocatechin gallate prevents cardiomyocytes from pyroptosis through lncRNA MEG3/TAF15/AIM2 axis in myocardial infarction
Chin Med
December 6, 2023
Chaoshi Qin, Tingting Wang, Ni Qian, Jing Liu, Rong Xi, Qing Zou, Hui Liu, Xiaolin Niu
were boiled in Na-citrate buffer for antigen retrieval, followed by incubating with anti-AIM2 (
1:500
,
ab93015
,
Abcam
) at a dilution of
1:200
overnight. Afterward, slices counterstained with hematoxylin, dehydrated
(2)
Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection
Journal of Virology
October 31, 2023
Yongqi Li, Yang Yang, Tianyang Li, Zhengmin Wang, Chunfeng Gao, Rilin Deng, Faxiang Ma, Xinyang Li, Licong Ma, Renyun Tian,
et al.
Slides were then incubated with LAMP-1 antibody (Catalog: ab289548, Abcam) or AIM2 antibody (Catalog:
ab93015
,
Abcam
) followed by Alexa Fluor-488-labeled secondary antibody (Catalog:
A-11029
or
A-11034
,
Invitrogen
).
(3)
Mesenchymal stem cell suppresses the efficacy of CAR-T toward killing lymphoma cells by modulating the microenvironment through stanniocalcin-1
eLife
February 13, 2023
Rui Zhang, Qingxi Liu, Sa Zhou, Hongpeng He, Mingfeng Zhao, Wenjian Ma
antibodies: rabbit anti- IL-1β (
Abcam
,
ab9722
), anti-Caspase-1 p20 (
Bioss
,
bs-10442R
), AIM2 (
Abcam
,
ab93015
),
IDO
(
Bioss
,
bs-15493R
),
PD-L1
(
Bioss
,
bsm-54472R
), and mouse anti-GAPDH (Santa Cruz) primary antibodies.
(4)
A Weakly Supervised Deep Learning Method for Guiding Ovarian Cancer Treatment and Identifying an Effective Biomarker
Cancers (Basel)
March 24, 2022
Ching-Wei Wang, Yu-Ching Lee, Cheng-Chang Chang, Yi-Jia Lin, Yi-An Liou, Po-Chao Hsu, Chun-Chieh Chang, Aung-Kyaw-Oo Sai, Chih-Hung Wang, Tai-Kuang Chao
(PBS) and then incubated for one hour at room temperature with antibodies of AIM2 (
1:500
) (
Abcam
, cat#
ab93015
, Cambridge, UK), NLRP3 (
1:300
) (
Millipore
, cat#
ABF23
, Burlington, VT, USA), C3 (
1:1000
) (
Abcam
, cat#
ab200999
,
(5)
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition
Cell death & disease
February 21, 2022
Zhang T, Wu DM, Luo PW, Liu T, Han R, Deng SH, He M, Zhao YY, Xu Y.
anti-Caspase-1 (
ab179515
),
anti-GSDMD
(
ab219800
),
anti-GSDMD
-N (
ab215203
), anti-ASC (
ab180799
) and anti-AIM2 (
ab93015
) (
Abcam
, Cambridge, UK); anti-γH2AX (
9718
) (
CST
, Danvers, MA, USA);
anti-PIF1
(
19006-1-AP
), anti-
BRCA1
(6)
Activation of the NLRP3 inflammasome and elevation of interleukin-1β secretion in infection by sever fever with thrombocytopenia syndrome virus
Scientific Reports
February 16, 2022
Zhifeng Li, Jianli Hu, Changjun Bao, Chengfeng Gao, Nan Zhang, Carol J. Cardona, Zheng Xing
rabbit anti-IL-1β (
sc-7884
) were purchased from
Santa Cruz Biotechnology
(Santa Cruz, CA). Anti-AIM2 (
ab93015
),
anti-NLRP1
(
ab98181
), and anti-NLRC4 (
ab99860
) antibodies were purchased from
Abcam
(Cambridge, UK).
(7)
Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway
Biomedicines
January 28, 2022
Kevin Harkin, Josy Augustine, Alan W. Stitt, Heping Xu, Mei Chen
Antibody,Concentration,Company,Catalogue ID,Species AIM2,
1:50
,
Abcam
,
AB93015
,Rb
CASP11
,
1:50
,
Thermofisher Scientific
,
PA5-20108
,Rb
Donkey
anti-Rabbit Alexa Fluor 488,
1:300
,
Jackson ImmunoResearch
(8)
Probenecid-Blocked Pannexin-1 Channel Protects Against Early Brain Injury via Inhibiting Neuronal AIM2 Inflammasome Activation After Subarachnoid Hemorrhage
Frontiers in neurology
January 1, 2022
Zheng Y, Tang W, Zeng H, Peng Y, Yu X, Yan F, Cao S.
nonfat dry milk buffer for 2 h and then incubated overnight at 4°C with the primary antibody for AIM2 (
ab93015
,
1:1,000
,
Abcam
), pannexin-1 (
ab124131
,
1:1,000
,
Abcam
),
ASC
(
ab155970
,
1:1,000
, Abcam), caspase-1 (
ab1872
,
(9)
Establishment of a prognosis Prediction Model Based on Pyroptosis-Related Signatures Associated With the Immune Microenvironment and Molecular Heterogeneity in Clear Cell Renal Cell Carcinoma
Frontiers in Oncology
November 5, 2021
Aimin Jiang et al.
Changzheng ccRCC tissue
microarray
using antibody purchased from the
Abcam
company (PYCARD, ab283684; AIM22,
ab93015
; IL6,
ab9324
;
GSDMB
,
ab235540
; TIRAP,
ab17218
; diluted at
1:100
–
1:200
). The Oncomine database (https://www.oncomine.org/resource/login.html)
(10)
Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
Nature communications
May 18, 2021
Wang LQ, Liu T, Yang S, Sun L, Zhao ZY, Li LY, She YC, Zheng YY, Ye XY, Bao Q,
et al
.
agarose (
20399
) were from
Pierce
.
Anti-Bip
(cat# AB310) was from Beyotime Technology. Anti-AIM2 (cat#
ab93015
) and anti-COX-IV (cat#
ab16056
) was from
Abcam
. Anti-ASC (cat# sc-271054), anti-caspase-1 (cat# sc-515),
(11)
Absent in melanoma 2 suppresses gastric cancer cell proliferation and migration via inactivation of AKT signaling pathway
Scientific reports
April 15, 2021
Wang D, Zou J, Dai J, Cheng Z.
manufacturer’s instructions through the use of a primary antibody recognizing
human
AIM2 (dilution
1:200
; #
ab93015
,
Abcam
).
Staining
intensity was classified as either 0 (no
staining
), 1 (weak
staining
), 2 (moderate
(12)
AIM2 inhibits colorectal cancer cell proliferation and migration through suppression of Gli1
Aging (Albany NY)
January 15, 2021
Menglin Xu, Junfeng Wang, Haoran Li, Zhengrong Zhang, Zhengwu Cheng
dioxide, followed by incubating with the primary antibodies recognizing
human
AIM2 (dilution
1:200
; #
ab93015
,
Abcam
) or
human
Gli1 (dilution
1:200
; #
ab15179
,
Abcam
) overnight at 4° C. Next day, the sections were
(13)
Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection
Journal of Experimental Medicine
January 4, 2021
Christina Megli, Stefanie Morosky, Dhivyaa Rajasundaram, Carolyn B. Coyne
(
13833
) rabbit monoclonal antibodies were purchased from
Cell Signaling Technology
. Rabbit anti-AIM2 (
ab93015
), cleaved IL-1β (
ab2105
), and
NLRP3
(
ab214185
) were purchased from
Abcam
. Rabbit anti-GAPDH (
sc-25778
)
(14)
Dihydroartemisinin inhibits activation of the AIM2 inflammasome pathway and NF-κB/HIF-1α/VEGF pathway by inducing autophagy in A431 human cutaneous squamous cell carcinoma cells
International journal of medical sciences
January 1, 2021
Wang Y, Li Z, Teng M, Liu J.
electrochemiluminescence detection system. The antibodies used in this study were rabbit anti-AIM2 (
1:1,000
;
ab93015
,
Abcam
, Cambridge, UK), rabbit
anti-IL-1β
(
1:1,000
;
16806-1-AP
,
Proteintech
, Rosemont, IL, USA), rabbit
(15)
Molecular stratification by BCL2A1 and AIM2 provides additional prognostic value in penile squamous cell carcinoma
Theranostics
January 1, 2021
Xingliang Tan et al.
interstitial cells and 5 for extremely strong). The antibodies and dilutions were as follows: AIM2 (
ab93015
,
Abcam
,
1:250
) and BCL2A1 (CY5582, Abways,
1:100
). The cut-off value was calculated using X-Tile software
(16)
Establishment of tumor inflammasome clusters with distinct immunogenomic landscape aids immunotherapy
Theranostics
January 1, 2021
Liang Q, Wu J, Zhao X, Shen S, Zhu C, Liu T, Cui X, Chen L, Wei C, Cheng P,
et al
.
ab213524
), mPD-L1 (
Abcam
,
ab213480
), hNlrp3 (
Abcam
,
ab214185
), mNlrp3 (
Abcam
,
ab270449
), hAim2 (
Abcam
,
ab93015
), mAim2 (
Proteintech
,
66902-1-Ig
), GAPDH (PTG, 60004-1), hCleaved Caspase 1 (CST, D57A2), mCleaved Caspase-1
(17)
Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes
Science Advances
March 6, 2020
Aramys S. Reis et al.
(
1:500
;
ab115537
), rabbit polyclonal anti-ASC (
1:500
;
ab47092
), and rabbit polyclonal anti-AIM2 (
1:250
;
ab93015
) (all from
Abcam
, UK) and with a
mouse
monoclonal anti–α-tubulin
clone
B-5-1-2 antibody (
1:10,000
;
T5168
;
(18)
HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways
International journal of molecular medicine
January 1, 2020
Wang J, Li R, Peng Z, Hu B, Rao X, Li J.
min to clear away endogenous peroxidase, incubated at polyclonal anti-
AIM2
antibody (
1:100
; cat. no.
ab93015
;
Abcam
) at 4°C overnight and then, incubated in a horseradish peroxidase (HRP)-linked anti-rabbit secondary
(19)
Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock
Frontiers in immunology
January 1, 2020
Sakaguchi N, Sasai M, Bando H, Lee Y, Pradipta A, Ma JS, Yamamoto M.
was obtained from
Proteintech
. Antibody against β-COP (
ab2899
) were purchased from
Abcam
. Anti-Aim2 (
ab93015
) was purchased from Abcam. Anti-NLRC4 (
06-1125
) was purchased from
Millipore
. For
immunofluorescence
(20)
Porphyromonas gingivalis
-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4
Frontiers in microbiology
January 1, 2020
Ding PH, Yang MX, Wang NN, Jin LJ, Dong Y, Cai X, Chen LL.
anti-NLRP12 (diluted
1:50
; #
37750
;
Signalway Antibody
), anti-absent in melanoma 2 (AIM2) (diluted
1:50
; #
ab93015
;
Abcam
),
anti-IL-1β
(diluted
1:200
; #
16806-1-AP
; Proteintech), anti-ASC (diluted
1:200
; #
10500-1-AP
;
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Anti-AIM2 antibody from Abcam
Supplier Page
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